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KMID : 0043319810040010001
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Archives of Pharmacal Research
1981 Volume.4 No. 1 p.1 ~ p.8
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Determination of the Optical Isomers of Ethmbutol (Myambutol) and 2-Amino-1-butanol by Gas-liquid Chromatography
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Kim YS
Youm JR/Park MK/Paik NH
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Abstract
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Our need for a convenient method of analytical estimation of the precise optical purity of d-2-aminobutanol (d-2AB) and d-ethambutol has prompted us to examine in detail the preparation and G.L.C. separation of the N-TFA-L-prolyl derivatives of their optical isomers (d-and l-2AB,d-, meso-and l-ethambutol). Silicon OV-1 columns were used for the G.L.C. separation.
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